Frequency-specific neuromodulation of local and distant

Por um escritor misterioso

Descrição

A growing literature has focused on the brain’s ability to augment processing in local regions by recruiting distant communities of neurons in response to neural decline or insult. In particular, both younger and older adult populations recruit bilateral prefrontal cortex (PFC) as a means of compensating for increasing neural effort to maintain successful cognitive function. However, it remains unclear how local changes in neural activity affect the recruitment of this adaptive mechanism. To address this problem, we combined graph theoretical measures from functional MRI (fMRI) with diffusion weighted imaging (DWI) and repetitive transcranial magnetic stimulation (rTMS) in order to resolve a central hypothesis: how do aged brains flexibly adapt to local changes in cortical activity? Specifically, we applied neuromodulation to increase or decrease local activity in a cortical region supporting successful memory encoding (left dorsolateral prefrontal cortex or DLPFC) using 5Hz or 1Hz rTMS, respectively. We then assessed a region’s local within-module degree (WMD), or the distributed between-module degree (BMD) between distant cortical communities. We predicted that (1) local stimulation-related deficits may be counteracted by boosting BMD between bilateral PFC, and that this effect should be (2) positively correlated with structural connectivity. Both predictions were confirmed; 5Hz rTMS increased local success-related activity and local increases in PFC connectivity, while 1Hz rTMS decreases local activity and triggered a more distributed pattern of bilateral PFC connectivity to compensate for this local inhibitory effect. These results provide an integrated, causal explanation for the network interactions associated with successful memory encoding in older adults.
Frequency-specific neuromodulation of local and distant
Frequency-specific transcranial neuromodulation of alpha power
Frequency-specific neuromodulation of local and distant
Rhythmic TMS or fluctuating tCS (aka tACS) have been used to
Frequency-specific neuromodulation of local and distant
Network-specific metabolic and haemodynamic effects elicited by
Frequency-specific neuromodulation of local and distant
Magnetic nanomaterials‐mediated neuromodulation - Lu - 2023
Frequency-specific neuromodulation of local and distant
Biomedicines, Free Full-Text
Frequency-specific neuromodulation of local and distant
Frontiers Enhancement of Frequency-Specific Hemodynamic Power
Frequency-specific neuromodulation of local and distant
Dynamic θ Frequency Coordination within and between the Prefrontal
Frequency-specific neuromodulation of local and distant
Frequency-Dependent Action of Neuromodulation
Frequency-specific neuromodulation of local and distant
Neuronal activity under transcranial radio-frequency stimulation
Frequency-specific neuromodulation of local and distant
A) One-dimensional representation of patchy connections in human
Frequency-specific neuromodulation of local and distant
Functional changes in prefrontal cortex following frequency
Frequency-specific neuromodulation of local and distant
Local and distant cortical responses to single pulse intracranial
de por adulto (o preço varia de acordo com o tamanho do grupo)